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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
STX-0119 Influence on tumor growth Tumor volume 40.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on tumor growth Tumor volume 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on tumor growth Body weight 40.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on tumor growth Body weight 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on protein activity in tumor tissue Western Blot 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu p-STAT3
STX-0119 Influence on protein activity in tumor tissue Western Blot 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu p-STAT3
STX-0119 Influence on protein activity in tumor tissue Western Blot 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu STAT3
STX-0119 Influence on protein activity in tumor tissue Western Blot 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu STAT3
STX-0119 Influence on dowstream target genes expression in tumor tissue Western Blot 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on dowstream target genes expression in tumor tissue Western Blot 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on dowstream target genes expression in tumor tissue Western Blot 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on dowstream target genes expression in tumor tissue Western Blot 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on dowstream target genes expression in tumor tissue Western Blot 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on dowstream target genes expression in tumor tissue Western Blot 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on dowstream target genes expression in tumor tissue Western Blot 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on dowstream target genes expression in tumor tissue Western Blot 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on protein activity in tumor tissue Hematoxylin and eosin staining 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on protein activity in tumor tissue Immunostaining 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on protein activity in tumor tissue Immunostaining 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Influence on protein activity in tumor tissue Immunostaining 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu p-STAT3
STX-0119 Influence on protein activity in tumor tissue Immunostaining 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu STAT3